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LEAFY target genes reveal a link between flower development and biotic stimulus response (III)
Cara Michele Winter, University of Pennsylvania, Philadelphia, Pennsylvania (caramw@mail.med.upenn.edu)
Experiment design (8 hybridizations)
genotype
•LFY-GR •WT

This experiment has been imported by PLEXdb from NCBI GEO (GSE28062)

Series_summary:
The transition from vegetative growth to flower ...[complete overview]

Experiment     Expression     Hybridizations & Samples     Quality Control     Compare Treatments     Downloads    

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Experiment Name: LEAFY target genes reveal a link between flower development and biotic stimulus response (III)
Accession No: AT125
Microarray: ATH1-121501
Visibility: public
Experiment Type:
Experiment Factor(s):
genotype
•LFY-GR   •WT
Quality Control: biological replicates
Treatment summary:
 genotype  # replicates
 LFY-GR  4
 WT  4
Total hybridizations: 8
Description: This experiment has been imported by PLEXdb from NCBI GEO (GSE28062)

Series_summary:
The transition from vegetative growth to flower formation is critical for the survival of flowering plants. The plant-specific transcription factor LEAFY (LFY) has central, evolutionarily conserved roles in this process, both in the formation of the first flower and later in floral patterning. We performed genome-wide binding and expression studies to elucidate the molecular mechanisms by which LFY executes these roles. Our study reveals that LFY directs an intricate regulatory network in control of floral homeotic gene expression and, unexpectedly, controls the expression of genes regulating the response to external stimuli in Arabidopsis. We further show that LFY dampens responses to a bacterial MAMP (microbe-associated molecular pattern) and to pathogen challenge. Our findings suggest a molecular mechanism for the coordination of reproductive stage development and disease response programs in plants. Regulation of these distinct survival programs by a single transcription factor may ensure optimal allocation of plant resources for reproductive fitness.
Expression array analysis used to identify genes differentially expressed upon LFY induction in 9-day-old shoot apices.

Series_overall_design:
Expression array analysis of 9-day-old 35S::LFY-GR dexamethasone-treated seedlings compared to 9-day-old WT dexamethasone-treated seedlings. Four biological replicate samples.


PLEXdb Curator's Note:
This SubSeries along with GSE28060 and GSE28061 are part of the GEO SuperSeries GSE28063 and are not imported because they are Chip-chip data sets.
Publication: 'LEAFY target genes reveal floral regulatory logic, cis motifs, and a link to biotic stimulus response.', Winter CM, Austin RS, Blanvillain-Baufumé S, Reback MA, Monniaux M, Wu MF, Sang Y, Yamaguchi A, Yamaguchi N, Parker JE, Parcy F, Jensen ST, Li H, Wagner D.
Dev Cell 2011 Apr 19;20(4):430-43.
pubmed: 21497757
Created: 2012-02-16 10:02:20
Last Update: 2012-02-23 11:26:08
Released: 2012-02-24
GEO Accession GSE28062
Submitter: PLEXdb Curator
Name: Cara Michele Winter
Institution: University of Pennsylvania, Philadelphia, Pennsylvania
Head of Laboratory: Doris Wagner
email(s):
Homepage:

 
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